What's on the Hill:
Potrero Hill has sun when most of San Francisco is foggy. You'll see when you come. Walking distance to lots of great restaurants( Aperto's, Baraka, Goat Hill Pizza, Eliza's, Chez Papa, Chez Maman for example) and coffee houses (Thinker's Cafe and Farley's). Near a brand new Whole Foods, the California Culinary Academy, and UCSF's new Mission Bay facility
The Design center is just at the bottom of the hill. Nearby you'll also find a Trader Joe's, REI.
The 19 Polk bus line runs nearby to take you to Pier 39 or downtown
What's Near:
San Francisco offers a wide array of diversions to suit many interests. Suggested activities include renting a bike at Pier 40 and ride along the Embarcadero all the way to Pier 39 or even across the Golden Gate bridge. Take the ferry back from Sausalito. On Saturday's, there's the farmer's market at the Embarcadero (Also on Thursday evenings).
The Marin headlands and Muir Woods are also not far. Napa and Sonoma for wine tasting make for a great day excursion.
Those with Children:
McKinley park, a few blocks away, is a great playground for children and provides spectacular views for parents. See information on bedrooms (including additional notes) for accommodations for small children.
Other Activities:
SF Giants ball park and Candlestick (49ers) nearby
Learn more about this holiday rental at the owner's website: